|The Reality is that people are sick. Chemicals are making them sick.
Doctors and researchers in the halls of the best Medical Facilities are taking sides.
Examples are in this page, The Cigarette Science
page and the Duke AOEM page and a number of other
Medical facilities around the world.
There are at least 3 Doctors/researchers from Duke working with patients at Duke and across the street at Veterans Hospital. It is not our intention to build up or put down any Medical Facility or Doctor, but to insist on
"Appropriate Medical Care for the Chemically Injured".
may have made a major breakthrough in understanding the toxicological
impact of multiple chemical exposures.
The discoveries may have a profound impact on the manufacturing, testing and warnings required for all chemicals sold in the United States.
A recent breakthrough in the understanding of Gulf War Syndrome may be changing scientific thinking and promoting further research on chemical synergy.
Researchers at the Duke University Medical Center and the Texas Southwestern Medical School reported in April, 1996 that the simultaneous exposure to topical insecticides [DEET and permethrin] and pyrido-stigmine bromide, a drug taken prophylactically to counteract toxic gas warfare agents, causes nervous system damage in chickens. The full written report is scheduled for publication in the May,1996 issue of the Journal of Toxicology and Environmental Health.
Both the team led by Robert Haley at Texas Southwestern and Modhamed Abou-Donia's group
of researchers at Duke found that the many symptoms experienced by Gulf War veterans,
including headaches, fatigue, aches, decreased attention and rashes, were similar to the
symptoms that presented in exposed chickens.
Chickens given any two chemicals became lethargic, unable to fly, lost weight and coordination and demonstrated tremors. For those administered all three chemicals, paralysis and death occurred.
This observed impact on nerve functioning is significant because survivors of the Gulf War who were exposed to these toxic agents also have demonstrated abnormal nerve function.
Further studies of Gulf War veterans who were exposed are being conducted at Texas Southwestern and are focusing on comparisons between physical findings in humans and those found in exposed chickens.
The results of that work is awaited by veterans, who until now, have been unable to show any relationship between their multiple symptoms and their exposures during the Gulf War.
More significantly, if these discoveries prove correct all manufacturers of commercial and household chemicals will be obligated to begin testing and instituting warnings of the synergistic effects of their products with other commonly used chemicals.
It is this new testing that holds promise for a better understanding of the impact of chemicals on health that has long been advocated by environmental activists, occupational health specialists, recipients of breast implants, those exposed to chlorinated hydrocarbons and sufferers of multiple chemical sensitivity.
The research of Steven F. Arnold and others at Tulane University published in June, 1996 shocked the scientific community. It proves that hormone-disrupting chemicals, known to cause mild effects, when used in combination produce significantly dramatic hormonal effects "Synergistic Activation of Estrogen Receptor with Combinations of Environmental Chemicals," 272 Science 1489-1492 (June7, 1996).
Combinations of two or three pesticides, which are commonly found in the environment at low levels, are up to 1600 times more powerful than any of the pesticides individually in their impact on hormones.
Some chemicals, which individually do not disrupt hormones, tremendously magnifies the ability of other chemicals to disrupt hormones. That was the finding with chlordane.
The study focused on endosulfan, chlordane, toxaphene and dieldrin, all of which impact a gene making estrogen in animals. Estrogen controls the formation and development of female organs and is strongly associated with both breast cancer and causing male sex organs to be deformed.
This is the beginning of a revolution in scientific knowledge that will profoundly
effect the way pesticides are screened and tested.
This research should prompt EPA to immediately require appropriate warnings. Regulations have long been based on studies of individual chemicals and their individual effects. Now EPA must take steps to regulate combinations of chemicals in order to assure appropriate levels of public safety.
The example of chlordane is particularly disturbing because it means that EPA,
manufacturers and the scientific community must now assess and evaluate of chemicals long
believed to have minor hormonal impacts. Accomplishing such testing will take years and
all the while significant damage to people will continue unabated.
The prevailing view that chemicals are safe until proven otherwise is no longer valid and all manufacturers must be required to prove the safety of their products when used in conjunction with other chemicals.
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